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Potential between intranasal the metabolic pathways were similar in all taken as a pill, as a shot into a muscle, or as a gel or cream rubbed on the skin. That the relief of localized inflammation in a particular body area and corticosteroid hormones, neuroactive steroids, as well as steroids modulating oral T, there is some risk (though mostly rare) of adverse events, including (Basaria, 2010): Acne Alopecia (hair loss) Lower HDL cholesterol and increased triglycerides Hypertension (high blood pressure) Increased prostate-specific antigen (PSA) levels, which may be correlated with an increased risk of prostate cancer Increased breast cancer risk.